english speech - lupus disease

so, here's my topic for english speech a week to go~ :

ABOUT LUPUS DISEASE

Lupus is a chronic inflammatory disease marked by its effect on various parts of the body, including the joints, skin, blood, and kidneys. It is a condition in which the body's immune system attacks its own cells and tissues, resulting in pain, inflammation, and often damage to organs.

In a normal condition, body immune system makes antibody to protect body against foreign substance in body, called antigens, but when a person has lupus, his or her body is unable to determine the difference between antigens and the individual's cells and body tissues. As such, the immune system creates antibodies against the individual's own tissues. These antibodies are called auto antibodies. That auto antibodies react with cells and tissues to form immune complexes. These immune complexes become concentrated in the body that causes pain, inflammation, and damage.

The number of lupus cases in females is higher than in males, it may indicate that the disease can be triggered by certain hormones. Physicians believe that hormones such as estrogen regulate the progression of the disease because symptoms tend to flare before menstrual periods and/or during pregnancy.

There are four types of lupus. The first type, discoid lupus, affects the skin. It is characterized by a rash that may appear on the face, neck, or scalp. Discoid lupus is diagnosed by performing a biopsy on the rash.

Systemic lupus is usually more severe than the discoid type, it is affecting nearly any organ or system of the body. For example, the disease can affect the skin, blood, nervous system, kidneys, heart, joints, and lungs. Some individuals with the disease have only one or two organs or tissues affected, while others may have many affected organs, systems, or tissues.

Drug-induced lupus is caused by the use of certain drugs. It is characterized by symptoms similar to those caused by the systemic form of the disease. Hydralazine and procainamide are the two drugs most frequently connected with the disorder.

The last type of lupus is neonatal lupus. Neonatal lupus affects newborns born to women who have systemic lupus. Their symptoms include heart defects, skin problems or problems with the liver.

Depending on the type of lupus, a wide range of symptoms may be experienced, from rashes, hair loss, and achy, swollen joints to fever, anemia, and abnormal blood clotting. Though the disease can affect many parts of the body, individuals usually experience symptoms in only a few organs. There is no known cure for lupus. However, medication and preventative-care treatments can help to minimize symptoms.